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    Home » What Is Preimplantation Genetic Testing? Should Embryos Have PGD or PGS? Part 2

    What Is Preimplantation Genetic Testing? Should Embryos Have PGD or PGS? Part 2

    How Do You Decide if Embryos Should Have PGD or PGS

    What is preimplantation genetic screening (PGS)?

    PGS involves testing an embryo for chromosomal abnormalities. Many embryos with chromosomal abnormalities will not lead to pregnancy or will result in a miscarriage. All women will have some eggs that are chromosomally abnormal. All men will have some sperm that is chromosomally abnormal. The percentage of embryos that are abnormal can be affected by many factors, including the age and health history of the parents.

    How is genetic testing performed?

    One or more cells are taken from an embryo and sent for genetic testing while the embryo is growing in the IVF laboratory. The testing can be done at different stages using different techniques. Techniques include fluorescent in situ hybridization (FISH), microarray, and single-nucleotide polymorphism (SNP).

    Techniques are constantly evolving and changing to be more accurate, easier to run, and give more information. Newer techniques that include microarray and genome sequencing are more common methods of genetic testing.

    Who should have PGD or PGS?

    PGD is for someone who has or is a carrier of a known genetic disorder. PGS may be recommended for someone with recurrent miscarriage, someone who is older or whose ovaries do not work as well as expected, or someone with multiple failed fertility treatments. Some couples also can choose to do PGS for personal reasons.

    This article is from the American Society for Reproductive Medicine and originally published on their website at: https://www.asrm.org/FACTSHEET_Preimplantation_genetic_testing/

    RSMC preforms PGD and PGS and the results are analyzed in our onsite lab. For more information, please e-mail info@fertile.com.

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